Reinvestigation of the roles of the carboxyl groups of glutathione with yeast glyoxalase I. Implications as to the mechanism and coenzymic role of glutathione.

Direct Demonstration by H.N.M.R. spectrometry of the stereoselectivity of yeast Glyoxalase l towards the Diastereomeric forms of the a-ketoaldehyde - Glutathione Hemithioacetal

Isolation of indigenous Glutathione producing Saccharomyces cerevisiae strains

Background: Glutathione (GSH) is a non-protein thiol compound, which plays an important role in the response to oxidative stress and nutritional stress. The aim of this study was to isolate indigenous S. cerevisiae strains capable of effectively produce GSH. Methods: One hundred-twenty sweet frui...

High Performance Liquid Chromatography Coupled with Pre-column Derivatization for Determination of Oxidized Glutathione Level in Rats Exposed to Paraquat

Glutathione (GSH) is one of the most important antioxidants that plays an essential role in detoxification of reactive oxygen species (ROS) which oxidizes to glutathione disulfide (GSSG). Paraquat (PQ), awidely used herbicide, causes pulmonary injury with the productionof ROS. Excessive ROS accumulation as a consequence of PQ exposure are frequently targeted by GSH thereby oxidative stress lead...

High Performance Liquid Chromatography Coupled with Pre-column Derivatization for Determination of Oxidized Glutathione Level in Rats Exposed to Paraquat

Glutathione (GSH) is one of the most important antioxidants that plays an essential role in detoxification of reactive oxygen species (ROS) which oxidizes to glutathione disulfide (GSSG). Paraquat (PQ), awidely used herbicide, causes pulmonary injury with the productionof ROS. Excessive ROS accumulation as a consequence of PQ exposure are frequently targeted by GSH thereby oxidative stress lead...

تأثیر شیرابه میوه گیاه خرمندی بر میزان گلوتاتیون کبدی در حیوانات مواجه یافته با عصاره آلکالوئیدی گیاه پیرگیاه

Background and purpose: Glutathione is one of the main antioxidants in animals which can protect against hazardous oxidative substances. Diospyros lotus consisted of antioxidants such as flavonoids and naphthoguinones which can influence the glutathione levels. On the other hand, Senecio vulgaris is expected to change the glutathione level, because of possessing toxic and oxidative compounds ca...